Anti-Human CD366, FITC (Clone: 1E3)检测试剂
¥2,960.00
- 分子靶点:CD366, TIM3, HAVCR2
- 种属:人 (Human)
- 标记:FITC
- 亚型:Rat IgG1
- 克隆号:1E3
在售SKU, F1136601, 70-F1136601-25, 70-F1136601-100
描述
商品名 |
Anti-Human CD366, FITC (Clone: 1E3)检测试剂 |
---|---|
靶点 | |
标记 |
FITC |
仪器 |
适用488nm激光器的流式细胞仪 |
亚型 |
Rat IgG1 |
克隆号 |
1E3 |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例


图 - CD3、CD28抗体诱导的人PBMC染色左图为Mouse IgG1 Isotype control, FITC和Anti-Human CD4, APC的结果,右图为Anti-Human CD366, FITC(F1136601)和Anti-Human CD4, APC的结果,以全部细胞设门。
分子信息
HAVCR2 分子靶点信息概述
- 分子名:HAVCR2, hepatitis A virus cellular receptor 2
- 基因家族:V-set domain containing
- 别名:Tim-3; TIM3; FLJ14428; TIMD3; CD366
- 全称:T-cell immunoglobulin mucin family member 3
HAVCR2 分子靶点综述
TIM3(甲型肝炎病毒细胞受体2,HAVCR2,T细胞免疫球蛋白)由281个氨基酸组成,类型为1的Th1特异性细胞表面糖蛋白,在终末分化的CD4 + Th1和CD8 + Tc1上表达细胞。TIM3由IgV样结构域,胞外区域的粘蛋白样结构域和胞质区域的保守的酪氨酸磷酸化基序组成。TIM3参与巨噬细胞的活化和自身免疫性疾病的发生。此外,TIM3介导的免疫反应,并促进免疫耐受。
人 Human HAVCR2 分子靶点信息
- 分子名:HAVCR2, hepatitis A virus cellular receptor 2
- 别称:
- CD366
- FLJ14428
- HAVcr-2
- kidney injury molecule-3
- KIM-3
- SPTCL
- T cell immunoglobulin mucin 3
- T cell immunoglobulin mucin-3
- T-cell immunoglobulin and mucin domain-containing protein 3
- T-cell immunoglobulin mucin family member 3
- T-cell immunoglobulin mucin receptor 3
- T-cell membrane protein 3
- Tim-3
- TIM3
- TIMD-3
- TIMD3
- 基因序列:NCBI_Gene: 84868
- 蛋白序列:UniProtKB: Q8TDQ0
人 Human HAVCR2靶点分子功能(预测)
Predicted to enable metal ion binding activity. Involved in several processes, including natural killer cell tolerance induction; negative regulation of leukocyte activation; and regulation of cytokine production. Located in cell surface. Implicated in hepatocellular carcinoma and renal cell carcinoma. Biomarker of cystic fibrosis and pulmonary tuberculosis.